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Codis (aspirin, codeine) provides relief from mild to moderate pain, as well as reduces fever and inflammation. The medication is safe for use in patients 16 year of age and up. Patients who are under 16, who have a major medical condition, or who are very elderly should discuss use with a doctor; adjusted dosage may be required.

Like many pain relievers, this medication comes in tablets. Note, however, that Codis tablets should be dissolved in water. The resulting medicated water is then consumed.

Fast & Effective Pain Relief

Codis combines the pain-reducing properties of aspirin with the narcotic effects of codeine. Together the two ingredients are far more potent at eliminating pain. Codis is often used to provide relief from:

• Headaches
• Migraines
• Arthritis
• Backache
• Toothaches
• Menstrual cramps
• Fibrositis
• Neuralgia
• Strains or sprains
• Other injuries

Relief usually begins 10 to 30 minutes after administration, and lasts around 6 hours. Additional doses can be taken every 4 to 6 hours as-needed to manage pain.

While often used in chronic conditions such as arthritis, Codis is typically used for short-term flare-ups, rarely for longer than three consecutive days. Longer use can produce a few complications, most notably:

• Continued use may promote tolerance to the medication, reducing its effectiveness;
• Use beyond three days increases risk of physical addiction, which may produce physical withdrawal symptoms when use stops.

If treating chronic pain, tolerance can often be prevented by alternating between different types of medication. However, though codeine is often used in long-term pain management, it is generally not a good idea to take the high levels of aspirin found in Codis over the long-term.

Dosage & Administration

Each Codis Tablet contains 500 mg aspirin and 8 mg codeine. As mentioned above, Codis tablets are designed to be dissolved in water prior to consumption.

Administration is simple:

• Dissolve 1 or 2 tablets in a glass of water and consume immediately.
• Repeat as-needed every 4 to 6 hours.
• Do not exceed 8 tablets in 24 hours.

Codis can cause drowsiness in some patients; use with caution until effects are known. If pain worsens, or is still severe enough to require treatment after several days, a doctor should be consulted.

Warnings & Adverse Effects

As is the case with most medications, there is a chance of experiencing side effects from Codis. Relatively common side effects are usually mild and not cause for concern, including:

• Constipation
• Stomach upset
• Dizziness
• Drowsiness
• Euphoria
• Tinnitus
• Vertigo

Rarely more serious side effects are experienced. Using large doses of Codis, or using the medication long-term, increases risk of serious adverse reactions. Warning signs which warrant medical attention include:

• Difficulty breathing
• Blood in vomit or stools
• Severe abdominal pain
• Severe confusion
• Chest pain
• Fainting
• Seizures

Unborn or nursing babies and young children may develop potentially life-threatening complications, such as suppressed breathing, if exposed to codeine. Use in young children should be strictly avoided without medical supervision, and mothers who are breast-feeding or in the third trimester of pregnancy should avoid using Codis or any codeine product.

Patients with any preexisting medical condition should discuss Codis use with a doctor before starting treatment; it may not be suitable in all cases.

Codis is known to interact with a wide range of other medications, supplements and recreational drugs, including:

• Sedatives, including alcohol and marijuana
• Blood thinners
• Antidepressants
• Antipsychotics
• Some diuretics
• Some antibiotics
• Some diabetes medications
• Some cancer medications

There are many other medications which may cause complications or lose effectiveness if mixed with Codis. Check with a doctor or pharmacist before mixing treatments.

Note that Codis contains relatively large amounts of aspirin. Side effects of aspirin also apply to Codis. Check labels of other medications being taken, particularly cold and flu remedies (in which aspirin is a common ingredient), to avoid taking too much aspirin.