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Country
  • India
Brand
  • Amifru
Strength
  • 5mg/40mg
Name Country Strength Pack Size USD Cart
Amifru - amiloride/furosemide - 5mg/40mg - 100 Tablets Diurisa/​Amifru amiloride/furosemide Brand India 5mg/40mg 100 Tablets DR $59.99 Add

Medicines have benefits and some have risks. Always read the label and use only as directed. If symptoms persist or you have side effects see your health professional. Brands and generics both contain the same active ingredient(s) and are medically equivalent. Some brands are marketed under different names by the same manufacturing country depending on the country of origin.

Amifru (amiloride, furosemide) is a potent diuretic that helps remove excess water from the body. It's often the first-line treatment in patients with edema caused by congestive heart failure, and is used in a range of other applications, including:

  • Renal failure
  • Hepatic disease
  • Congestive heart failure
  • Hypertension
  • Hypokalemia
  • Fluid retention from other causes

Amifru is effective due to its two active ingredients, which are:

  • Amiloride is a potassium-sparing diuretic which increases the amount of salts expelled in urine while decreasing the amount of potassium expelled.
  • Furosemide is a loop diuretic which also encourages the expulsion of salts, but does not inhibit release of potassium. Combining it with a potassium-sparing diuretic like amiloride helps ensure potassium levels will not become too low.

Both ingredients work similarly in removing salts from the body, which in turn inhibits excess water retention. Furosemide is the more powerful of the two ingredients, but it also removes potassium from the body; amiloride gives a bit of a boost to salt-removal while inhibiting potassium removal. The combination is a potent diuretic that won't cause potassium levels to be depleted to potentially-dangerous levels.

Diurisa should not be used in patients under 18 years of age; effects on still-developing bodies are unclear.

What to Expect from Amifru

Dosage of Amifru is best determined by a doctor, as numerous personal variables will need to be taken into account. As a general rule patients on other medications or who have other serious medical conditions should start with lower doses, increasing only if needed and tolerated. Otherwise healthy patients may start on moderate doses, and adjust up or down accordingly if needed.

Tablets may be taken once or twice per day, depending on dosage and response to treatment; some individuals have better results if dividing a single large dose into two smaller doses. Tablets should be taken with fluids and food.

Patients taking Amifru can expect a greater output of urine for the duration of treatment; while volume may also be increased, frequency of urination will almost certainly be. Patients should be prepared to adjust accordingly.

Treatment may continue for as long as it provides benefit. Regular doctor checkups to monitor potassium levels and otherwise monitor for developing side effects are highly recommended.

Possible Side Effects

Most patients tolerate Amifru well and do not experience serious side effects. Relatively common side effects might be experienced, however, including:

  • Dry mouth
  • Nausea
  • Diarrhea
  • Headache
  • Numbness
  • Tingling

The above are not cause for concern unless severe enough to be disruptive. In most cases they will stop occurring over time as the body adjusts to treatment.

Serious side effects are rare, but they do happen. Regular doctor checkups will help prevent serious complications. Seek medical attention at once if experiencing:

  • Blurry vision
  • Photosensitivity
  • Persistent ringing in the ears
  • Hearing loss
  • Excessive drowsiness
  • Confusion or altered mental state
  • Bleeding or bruising readily
  • Fever or chills
  • Excessive thirst
  • Muscle pain
  • Rapid heartbeat
  • Difficulty urinating
  • Difficulty breathing

Amifru may cause drowsiness; use caution until effects are known.

Since Amifru can elevate blood glucose levels, blood glucose should be monitored carefully in diabetics. The medication should not be used if metabolic acidosis or respiratory acidosis are present.

Amifru should not be taken in the event of severe sodium depletion, dehydration, or if kidney or liver function is impaired.

Ammifru is known to interact with other medications, including:

  • Salicylates, such as aspirin
  • Other diuretics
  • Antihypertensives
  • Antidepressants and antipsychotics
  • Many heart medications
  • Antibiotics and antifungals
  • Many painkillers
  • Antiepileptics

Double-check with a doctor or pharmacist if taking any other medications, and if the dosage of any medications are changed during treatment.

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