) is a medication in the triptan class of
drugs used to treat migraine headaches and the symptoms associated
with migraines, such as auras. In some forms it's also useful in
alleviating cluster headache pain.
Zomig is one of the best-selling migraine treatments in the world.
It is not effective on hemiplegic or basilar migraines, or tension
Stopping Migraines with Zomig:
While no one knows exactly why some people get migraines, it
known that when a migraine is happening certain blood
vessels in the brain become swollen. Zomig constricts those blood
vessels, relieving pressure on the brain. The medication also
blocks pain signals and inhibits production of chemicals believed
to contribute to symptoms such as auras, light sensitivity, or
Used properly, Zomig is effective for the majority of migraine
- Tablets are taken as needed when symptoms first begin. It will
not prevent a migraine from happening if taken prior to
- Ideal dosage will be determined by the physician prescribing
Zomig. Tablets come in 2.5 mg; usually 1 or 2 tablets is one
- Tablets can be split in half if a smaller dose is desired.
- Take tablets with water or some other fluid. Eating is not
necessary, but may help prevent nausea.
- If tablets are vomited up within 30 minutes of administration,
another dose should be taken.
- Effects are usually felt within 30 minutes, but peak at 2
- If the headache persists or returns after 2 hours, a second
dose may be taken as long as 10 mg are not exceeded in a 24 hour
A certain percentage of patients do not respond to Zomig. If this
medication proves ineffective against migraines, a doctor can
recommend other treatments to try.
Zomig is also available in orally dissolving tablets
(ODT) and in a nasal spray
Treating Cluster Headaches:
Like other triptan medications, zolmitriptan is somewhat helpful
for relieving cluster headache pain. However, tablet form is the
least effective means of administration for cluster headaches;
absorption into the blood stream is too slow.
Orally dissolving tablets are somewhat more effective than tablets,
but nasal spray is even more powerful and fast acting.
Cluster headache sufferers typically find the best relief with
triptan injections, such as offered by Imitrex
Zomig is not approved for cluster headache relief in all areas.
As with all medications there are certain risks associated with
Zomig use. Some patients are not ideal candidates and have a higher
chance of experiencing severe adverse reactions:
- History of liver, kidney, or heart disease
- Blood circulation problems
- Recent heart attack or stroke
- Very high blood pressure
- High risk of developing coronary heart disease
Never mix migraine treatments unless instructed to do so by a
physician -- too much of this type of drug may cause potentially
It is not known if Zomig is harmful to unborn or nursing babies. It
should be used with extreme caution by pregnant or nursing
Zomig does interact with some other medications. Though serious
side effects are unlikely, effectiveness of one or more the
medications may be reduced. This is particularly true of
antidepressants. For a complete list of possible interactions, read
the leaflet included with the product or speak to a doctor or
Most side effects are mild and pass quickly:
- Skin sensitivity
- Muscle aches
- Nausea or vomiting
- Rapid heart beat
- Dry mouth
Rarely some patients are allergic to the ingredients in this
medication. Symptoms include swelling of the face, tongue or
throat, difficulty breathing, or a rash or hives. Allergic
reactions warrant emergency medical attention.
Active ingredient: zolmitriptan
Inactive ingredients: lactose anhydrous, macrogols, sodium
starch glycolate, hypromellose, titanium dioxide, microcrystalline
cellulose, magnesium stearate, iron oxide yellow CI77492