» Read our 5-star reviews on:

» View All Online Doctor Products! «

Buy Macrodantin

Subscribe & Save Big

Sign up for automatic refills, and save big. Here's how much:

$500+ a month20% savings*
$250-$499 a month15% savings*
$100-$249 a month10% savings*
$1-$99 a month5% savings
* Individual orders over $100 USD receive free standard shipping. All ranges above in USD.
This product requires a prescription. Our online Dr can review your medical history and may issue a prescription renewal (at no extra cost). Online doctor products do not ship from New Zealand, but from a licensed affiliate international pharmacy (typically the UK).
Most sites charge $30-$40 for an online doctor fee per order - we do not charge a doctor fee.
Ships from the UK with tracking.

Macrodantin (nitrofurantoin macrocrystals) is an antibiotic used to treat or prevent bacterial infection in the bladder or urinary tract. It is effective against a wide range of bacteria, but because it concentrates in the bladder and has poor penetration elsewhere in the body, it is not very effective in other applications. It can be used in all ages and it also used in veterinary medicine.

There is some antibiotic resistance to Macrodantin but it is not as widespread as many other types of antibiotics. To help prevent further resistance from developing it's important to complete treatment with this or any other antibiotic, antifungal, or antiviral medication even if symptoms clear up.

Using Macrodantin to Treat Infections

Macrodantin is effective at treating infection of the bladder or urinary tract. It is useful against a range of bacteria commonly associated with such infections, including E. coli and several Staphylococcus and Streptococcus species.

This particular medication provides little benefit against infections in the kidneys or elsewhere in the body. It will not help with fungal or viral infections.

To treat infection in otherwise healthy adults:

  • 50 to 100 mg should be taken four times per day, spaced apart as evenly as possible.
  • Food or milk should be consumed with each dose to aid with absorption.
  • Treatment should continue for at least one week.
  • Treatment should continue for three days after the infection has cleared up.

Dosage depends on both the severity of the infection and patient weight. Likewise duration of treatment may vary; one week is sufficient in most cases, but sometimes it will take longer. Some improvement is usually noticed within a day or two of starting treatment. If there is little or no improvement after a week of taking Macrodantin a doctor should be consulted; it may not be a bacterial infection.

In younger patients dosage depends on weight; as a general rule, 5 mg of Macrodantin per kg of weight per day. As with adults, the total dose should be divided into four smaller doses, taken at evenly-spaced intervals throughout the day.

Using Macrodantin to Prevent Infection

Macrodantin is also used to prevent infection in patients at risk of acquiring an infection or who are simply prone to recurring infections. As a preventive measure treatment is much simpler:

  • Adults should take 50 to 100 mg once per day, typically at bedtime.
  • Children should be given 1 mg per kg of weight per day, at bedtime.
  • Food or milk should be consumed with each dose to aid with absorption.
  • Treatment may continue for as long as necessary, but there are risks associated with long-term use.

Though very rare---about 1 in 5000 patients---some individuals experience pulmonary (lung) complications if taking Macrodantin long-term. The risk is slightly higher in women and slightly higher in elderly patients. Symptoms are not necessarily noticeable until serious damage has been done, which may or may not be reversible. Patients using Macrodantin for more than a couple weeks should be alert for any change in lung function---such as unexplained frequent coughing, chest pain, difficulty breathing, or any other changes---and should attend regular doctor checkups to monitor for developing complications.

Side Effects

Most patients experience only mild side effects from Macrodantin, similar to those experienced while taking any antibiotic. Most common side effects include:

  • Abdominal discomfort
  • Nausea
  • Vomiting
  • Appetite loss
  • Headache
  • Diarrhea

The above symptoms are not cause for concern unless severe.

Macrodantin may cause the urine to be brown. This is normal and not cause for concern.

There is conflicting evidence as to the safety of Macrodantin on unborn or nursing babies. Pregnant or breastfeeding mothers should discuss potential risks with a doctor; in most places safer alternatives will be readily available.


100mg nitrofurantoin macrocrystals  Buy Macrodantin 30 Capsules - $57.66
Online Doctor
No current Rx required
Pack Sizes Strength Price Cart
Buy Macrodantin 30 CapsulesGeneric 100mg $57.66 Add
Buy Macrodantin 30 CapsulesGeneric 50mg $70.64 Add
Buy Macrodantin 90 CapsulesGeneric 100mg $116.77 Add
Buy Macrodantin 90 CapsulesGeneric 50mg $165.73 Add
Macrobid SR Pack Sizes Strength Price Cart
Buy Macrodantin 14 CapsulesBrand 100mg $43.25 Add
Niftas Pack Sizes Strength Price Cart
Buy Macrodantin 100 TabletsGeneric 50mg $59.99 Add
Prompt shipping from India.
Urifast Pack Sizes Strength Price Cart
Buy Macrodantin 100 CapsulesGeneric 100mg $44.00 Add
Prompt shipping from India.

Medicines have benefits and some have risks. Always read the label and use only as directed. If symptoms persist or you have side effects see your health professional.

You may also be interested in...
Cipro / ciprofloxacin
500mg - 100 Tablets $59.99 USD
Amoxicillin / amoxicillin capsule
500mg - 100 CAP $59.99 USD
Bactrim / trimethoprim/sulfamethoxazole
400mg/80mg - 100 Tablets $49.99 USD
Cialis / tadalafil
5mg - 100 Tablets $119.99 USD
Aciclovir / aciclovir
800mg - 105 Tablets $43.25 USD
Macrobid SR / nitrofurantoin macrocrystals
100mg - 14 Capsules $43.25 USD
Niftas / nitrofurantoin macrocrystals
50mg - 100 Tablets $59.99 USD
Urifast / nitrofurantoin macrocrystals
100mg - 100 Capsules $44.00 USD

Macrodantin Reviews

No one has reviewed MACRODANTIN yet, why not be the first!
Rating (Optional):
Enter Code Below:

post my review
more reviews available on:
Like us on Facebook and receive 10% off your next order!* New Zealand Pharmacy
 » is ranked 4.9 out of 5. Based on 2273 user reviews.
Site Map
* 10% one-time discount applies to orders over $100