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Imigran (sumatriptan succinate) is in the triptan class of drugs, widely used around the world to manage symptoms of migraine and cluster headaches. It is an abortive treatment, meaning it only stops symptoms that have already begun; it will not prevent new headaches from developing.

This medication should not be used in patients under age 18 or over age 65 without explicit doctor approval; there is a significantly higher risk of side effects.

Managing Migraines with Imigran

Imigran is predominately used to treat migraines, particularly in tablet form. It alleviates both pain and other symptoms, such as auras, nausea, and sensitivity to light and sound. Treatment is simple and straightforward:

  • Take one dose of Imigran at the earliest symptoms of a migraine.
  • If pain and/or other symptoms are not sufficiently alleviated, or the headache returns, a second dose may be taken after two hours.
  • Do not exceed 300 mg in a 24 hour period.
  • Tablets can be crushed, chewed or dissolved, but they are very bitter. Those who have difficulty swallowing tablets may want to consider Imigran Radis, which is designed to be dissolvable (but will still taste bitter).

Patients are usually started on 50 mg doses. Some individuals who have particularly severe migraines or who are simply less sensitive to Imigran may find 100 mg more effective. As with any medication, however, there is a risk of side effects and this risk is higher with higher doses; the lowest effective dose is preferable.

This medication tends to produce the best results if taken at the earliest signs a headache is developing, but Imigran will still provide benefit if taken at later stages. Effects start to be felt about 30 minutes after taking a dose.

For unclear reasons some patients simply don't respond to Imigran. If there is no improvement at all after the first dose, a second dose should not be taken. A doctor or pharmacist can suggest alternative options.

Imigran for Cluster Headaches

Triptan medications are one of the few effective options out there for cluster headache-suffers. With cluster headaches, taking the medication at the earliest symptoms is very important; the medication may not provide significant benefit if taken at later stages.

Because the timing is so critical with cluster headaches, tablets---which take about 30 minutes to start working---are usually not the ideal choice. They do work for some individuals, however; treatment is the same as for migraines (above).

Faster-acting Imigran options are:

Many patients are understandably averse to injections, but it is the most effective route for rapid pain relief in the majority of cluster headache-sufferers. It's also not as bad as many people imagine---it is injected subcutaneously (under the skin) rather than into muscle or the bloodstream; needles for this purpose are very short and thin, virtually painless.

Warnings & Side Effects

Patients with certain health conditions are at greater risk of experiencing complications when taking Imigran. Discuss risks with a doctor before use if there is a history of:

  • Poor blood circulation
  • Coronary heart disease
  • Angina
  • Seizures
  • High blood pressure
  • Heart attack or stroke
  • Liver or kidney impairment
  • Ischemic bowel disease

As with any medication there is a risk of side effects when using Imigran. Most are mild and pass quickly, including:

  • Flushing or feeling warm, particularly in the chest area
  • Mild dizziness or lightheadedness
  • Nausea or vomiting
  • Muscle cramps
  • Drowsiness

The above side effects are not cause for concern unless severe enough to be disruptive.

Imigran should not be used within a week of taking SSRIs, SNRIs, or MAOIs, and vice versa; do not take those medications within a week of using Imigran.


50mg sumatriptan succinate  Buy Imigran 6 Tablets - $115.39
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Brand Pack Sizes Strength Price Cart
Buy Imigran 6 Tablets 50mg $115.39 Add
Buy Imigran 6 Tablets 100mg $173.08 Add

Medicines have benefits and some have risks. Always read the label and use only as directed. If symptoms persist or you have side effects see your health professional.

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