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Co-Diovan (valsartan and hydrochlorothiazide)
is a treatment for high blood pressure usually prescribed for those
patients who did not respond well to treatment with valsartan
The two active ingredients in Co-Diovan complement each other,
resulting in a more powerful medication:
blood pressure reduces the workload of the heart and decreases the
risk of risk of stroke and blood vessel damage.
- Valsartan blocks a hormone called
angiotensin II, which regulates blood pressure and fluid balances.
When the hormone is blocked, blood vessels naturally widen and
urine production increases, both actions which help lower blood
- Hydrochlorothiazide is a diuretic which further
increases urine output by filtering salts out of the bloodstream,
an action which also removes water from the blood. The end result
is a lower overall volume of blood, which reduces blood
Using Co-Diovan to Lower Blood Pressure
Co-Diovan tablets range in strength from 80 to 320 mg of valsartan
and 12.5 to 25 mg of hydrochlorothiazide. Dosage strength will
depend on the patient and the severity of the high blood pressure
and should only be determined by a doctor. The lowest possible dose
is desirable to prevent adverse effects.
Following a few simple guidelines, treatment with Co-Diovan is
of treatment is highly variable. This medication is often given
when valsartan alone is not effective, when the cause of the high
blood pressure is unknown, and when efforts to lower blood pressure
through lifestyle changes are ineffective; all situations which
generally call for long-term treatment.
Never take more of this medication than prescribed, or combine it
with other blood pressure reducing treatments unless specifically
approved by a doctor. Severely low blood pressure is every bit as
dangerous as high blood pressure and can be fatal. Warning signs
include extreme dizziness and fainting. If this occurs, call for
medical help and, if possible, lie down until it
Precautions & Side Effects
While this medication may sound like a simple diuretic, the
alteration of salts and fluids in the blood can impact every bodily
system. In the interest of maximizing effectiveness and safety, be
aware of potential complications:
- Take once daily with fluids, preferably in morning as the
medication will increase urine production.
- Don't crush, dissolve, chew or otherwise damage tablets;
- The medication stays in the body for around 24 hours, so taking
it at the same time each day is ideal.
- It may be taken with or without food, but whichever route is
chosen should remain consistent.
- Full effects are felt after 2 to 4 weeks of treatment.
effects are rarely dangerous when other major health issues are not
present, including light-headedness, coughing, muscle pain and
tinnitus. Often these symptoms will disappear as the body adjusts
to treatment. Dehydration is also common during treatment. due to
increased urine production.
See the insert included with the product for a full list of side
- Check with a doctor or pharmacist before using other
medications with Co-Diovan; it is known to interact with many
prescription and non-prescription drugs.
- Alcohol should be used with caution during treatment; it may
further reduce blood pressure.
- This medication should not be used while pregnant or breast
feeding except in rare cases where benefits outweigh risks.
- Patients with severe liver or kidney disease, gout, difficulty
urinating, low salt levels, diabetes, immune system disorders, and
certain heart problems are at greater risk of serious side
- Co-Diovan may cause dizziness or drowsiness; use with caution
while driving or performing other complex tasks until you know how
the medication effects you.
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