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  • India
  • United Kingdom
  • Choltran
  • Colestyramine SF
Name Country Strength Pack Size USD Cart
Choltran - cholestyramine -  - 50 DOSES Questran/​Choltran cholestyramine Brand India 50 DOSES DR $99.99 Add
Colestyramine SF - colestyramine sf -  - 50  Doses Questran Lite Powder/​Colestyramine SF colestyramine sf Generic United Kingdom 50 Doses DR $111.70 Add

Medicines have benefits and some have risks. Always read the label and use only as directed. If symptoms persist or you have side effects see your health professional. Brands and generics both contain the same active ingredient(s) and are medically equivalent. Some brands are marketed under different names by the same manufacturer depending on the country of origin. Images are provided as a reference only, the received medicine may vary in packaging, color, pill shape, etc, from one batch to the next. For an item marked "generic" any quality brand may be sent, however you will always receive the active ingredients ordered in the strength(s) ordered.

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Questran (cholestyramine) is used in a variety of applications from lowering cholesterol to hastening the elimination of other medications from the body. It is often used as a cholesterol-reducing medication in cases where dietary changes alone have proven unhelpful. 

Though for the most part a remarkably safe treatment, patients with a history of intestinal blockages, diabetes, thyroid disorders, kidney or liver disease, chronic vitamin deficiency or chronic constipation should use with caution and doctor supervision. 

Conditions Treated 

Questran works by binding with bile it encounters in the intestines, preventing its reabsorption. Without treatment the bile would be reabsorbed and ultimately wind up back in the liver, where it would be secreted once again to aid digestion in the intestine. Bile which is not reabsorbed is instead excreted as waste.  

Bile elimination is helpful in a number of conditions: 

  • Lower LDL cholesterol - The liver uses cholesterol to produce bile. When large amounts of bile are already present, being reabsorbed and reused, the liver has little need to extract cholesterol from the blood to make new bile. By forcing the bile to be excreted, the liver has no choice but to remove cholesterol from the blood to make new bile, ultimately lowering cholesterol levels in the blood. 
  • Reduce itching associated with liver failure - When bile is reabsorbed through the intestine it enters the bloodstream, where the liver should extract it in preparation for the next secretion. When the liver is unable to extract bile from the bloodstream, quantities will build up in both the blood and the skin, a condition which produces severe itching. Removing excess bile with Questran will reduce or eliminate the itching. 
  • Reduce diarrhea from excess bile - Bile attracts water, and excess water in the intestine can cause diarrhea. After certain surgeries, such as gallbladder removal or shortening of the small intestine, as well as in some bowel conditions, such as irritable bowel syndrome, bile will collect in relatively large amounts, attracting excess water, which causes chronic diarrhea. Expelling the excess bile will reduce or eliminate the diarrhea. 
Additionally, in some circumstances Questran may be used to aid expulsion of other medications. Most common is leflunomide, a treatment for arthritis, which may linger in the body for years after treatment stops unless flushed out with a medication like Questran. 

Administering Questran 

This medication comes in a powder, either in packets or in a cannister with a measured scoop. Each packet or scoop represents one dose, or 2 grams of medication. Most patients are prescribed 4 to 8 grams per day, though it may be as high as 24 grams. Smaller doses may be taken once daily, but in most cases the total daily amount is split into 2 doses, and occasionally as many as 6. 

Preparation and administration is fairly straightforward:
  • Mix each dose into a non-carbonated beverage or a food with high liquid content, such as soup or applesauce.
  • For each single packet or scoop there should be 2 to 6 ounces of fluid; if taking 2 packets, mix with a minimum of 4 to 12 ounces of fluid.
  • Consume prepared mixture in entirety; do not hold the mixture in the mouth, doing so may cause tooth discoloration. 
  • Brush teeth after each dose to prevent tooth discoloration.
  • Drink plenty of additional fluids to prevent constipation.
  • Do not exceed prescribed dosage, doing so may cause severe constipation.
Questran Lite Powder (cholestyramine) is a bile acid sequestrant used in a variety of applications in which the inhibition of bile absorption in the intestine is desirable. The most common conditions it is used in include: 
  • Lowering LDL cholesterol levels
  • Reducing severs itching associated with liver failure
  • Reducing diarrhea associated with certain conditions or surgeries
  • Hastening the elimination of certain other medications
Unlike the original Questran, Questran Lite Powder contains the artificial sweetener aspartame rather than sugar. Aspartame contains phenylalanine, so clients with phenylketonuria should avoid Questran Lite Powder; regular Questran does not contain phenylalanine. 

Using Questran Lite Powder Effectively 

This product comes in single-dose packets or in a cannister with a measured scoop representing a single dose. Each dose contains 2 grams of medication. Most patients are prescribed 2 to 4 doses, or 4 to 8 grams, of medication daily. Rarely the dose may be as high as 24 grams. 

The overall daily dosage is usually split into 2 equal doses to be taken morning and evening, though smaller doses may be taken just once a day and larger doses may taken up to 6 times a day. 

To take Questran Lite Powder, simply mix the powder into a non-carbonated beverage, or alternatively a food with high liquid content such as soup. It may be taken with or without a full meal, and fluids may be warm or cold. Mixture should be consumed immediately and completely.  

There are a few things to keep in mind while using this medication to minimize side effects and maximize effectiveness: 
  • Each single dose should be mixed with a minimum of 2 to 6 ounces of fluid; if taking 2 doses, mix with 4 to 12 ounces of fluid, 3 doses, 6 to 18 ounces of fluid, and so on.
  • Do not hold the mixture in your mouth, as doing so may cause tooth discoloration. Likewise, always brush teeth after taking a dose.
  • Do not consume dry powder or take more than prescribed; doing so may cause severe constipation.
  • This treatment may prevent certain nutrients and other medications from being absorbed properly; taking supplements and other medications several hours before or after Questran Lite Powder will prevent absorption issues.
  • Drink extra fluids while using this product to prevent constipation.
Most patients taking Questran Lite Powder longer than a week or two are advised to supplement a daily multivitamin, as this medication may result in chronic vitamin A, D, E and K deficiency. 

Potential Side Effects & Complications 

Patients at risk of, or with a history of, intestinal blockages, diabetes, thyroid disorders, kidney or liver disease, gallstones, chronic vitamin deficiency or chronic constipation should discuss risks with a doctor before using this medication. 

The most common side effect with this treatment is constipation. As mentioned above, increasing fluid intake is the best way to prevent this from happening.  

Other than constipation, side effects are quite rare and most are harmless, including mild constipation or diarrhea, mild stomach upset, bloating, and itching around the anus. Very rarely more serious reactions occur, which call for emergency medical attention: 
  • Blood in urine or stools
  • Severe constipation
  • Severe stomach pain
  • Difficulty breathing
The effect of this medication on unborn or nursing babies is unknown, however, because it may interfere with vitamin absorption, it should be used only when absolutely necessary and with close doctor supervision. 

Regular doctor check-ups are advisable for all patients while using this medication, to both ensure it is working as intended and to monitor any possible subtle side effects, such as vitamin deficiency.



I have gotten sick from mold and used this to remove the toxins. This was the only way I could get the medicine on my own, since my Dr. was unable to help me with mold illness. It comes in 5 gm packet...s of which 4 gms is the active ingredient. I have ordered it many times. Once customs confiscated an order, all other orders arrived normally. I really appreciate having access to this important medicine!

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Oct 9, 2019



It's working great and it arrived earlier than stated. Would buy again!

Mar 18, 2016



I have had to take this medication for 20 years now and wouldn't last 6 months without it. I have colitis and no gallbladder (too much bile) and this binds the bile together so I can function nearly n...ormal instead of spending my life unable to eat.

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Dec 21, 2015



I have to take Questran every day it works and I could not lead a normal life without it

Sep 25, 2014

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