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Country
  • United Kingdom
Brand
  • Ebixa XR
Strength
  • 10mg
  • 20mg
  • Titration Pack
Name Country Strength Pack Size USD Cart
Ebixa XR - memantine hcl - 10mg - 28 Tablets Namenda XR/​Ebixa XR memantine hcl Brand United Kingdom 10mg 28 Tablets DR $131.28 Add
Ebixa XR - memantine hcl - Titration Pack - 28 Tablets Namenda XR/​Ebixa XR memantine hcl Brand United Kingdom Titration Pack 28 Tablets DR $153.15 Add
Ebixa XR - memantine hcl - 20mg - 28 Tablets Namenda XR/​Ebixa XR memantine hcl Brand United Kingdom 20mg 28 Tablets DR $233.38 Add

Medicines have benefits and some have risks. Always read the label and use only as directed. If symptoms persist or you have side effects see your health professional. Brands and generics both contain the same active ingredient(s) and are medically equivalent. Some brands are marketed under different names by the same manufacturing country depending on the country of origin.

Ebixa XR (memantine hydrochloride) is used to slow progression of Alzheimer's disease and restore some degree of cognitive function, particularly memory. It can be used in early-onset Alzheimer's provided the patient is at least 18 years of age.

This medication is also sometimes used to treat dementia with Lewy bodies (DLB), though this use is off-label in most locations and somewhat controversial. Ebixa XR has shown no benefit in vascular dementia.

Ebixa XR works best in moderate to severe Alzheimer's. Extensive studies have shown little benefit in mild Alzheimer's.

The XR in this product indicates it's extended release, compared to regular Ebixa. While regular Ebixa is often taken twice per day, Ebixa XR is just taken once. The main drawback is that regular Ebixa can be split but Ebixa XR must be swallowed whole.

What to Expect from Ebixa XR

Ebixa XR is an N-methyl-Daspartate (NMDA) receptor antagonist that works to protect NMDA receptors from damage caused by the neurotransmitter glutamate. At normal levels glutamate is not harmful, but at the altered levels found in Alzheimer's it is associated with brain degeneration.

In protecting NMDA receptors, Ebixa XR ultimately helps preserve memory and, to a lesser extent, learning ability. Patients often see improvements in:

  • Attention/focus
  • Memory
  • Orientation
  • Routine activities
  • Socializing
  • Speaking/communicating

It is not realistic to expect patients to revert to pre-Alzheimer's function. Some mental impairment will still be present; the more the condition has progressed, the worse it will be. However, many patients do experience significant benefit, including:

  • Increased independence
  • Reduced reliance on caretakers
  • Retained sense of self
  • Improved ability to communicate coherently
  • Improved quality time with loved ones

Note that Ebixa XR is not a cure; it only slows progression of Alzheimer's. The medication will not stop it from progressing entirely. Patients, loved ones, and caretakers should be aware that there will come a time when Ebixa XR no longer provides benefit.

Ebixa XR buys patients time and allows them to make the most of that time.

Taking Ebixa XR

For best results the condition should be diagnosed by a doctor prior to administering Ebixa XR. If Alzheimer's has been diagnosed, ideally a doctor familiar with the disease and medications to treat it will prescribe Ebixa XR. The medication is not for everyone.

If Ebixa XR has been determined to be suitable, treatment is as follows:

  • Start with 7 mg per day for 7 days.
  • Increase dosage to 14 mg per day for 7 days.
  • Increase dosage to 21 mg per day for 7 days.
  • Increase dosage to 28 mg per day and continue for as long as treatment provides benefit.
  • Do not exceed 28 mg per day without explicit doctor instruction.
  • Do not crush, chew, dissolve or otherwise damage tablets; they should be swallowed whole.

Ebixa XR is available in titration packs, which contain 7 of each tablet strength to get patients up to the target dose in one month.

Tablets are taken just once per day. They may be taken with or without food according to personal preference. Taking with food may help ease side effects like nausea.

If a dose is missed for more than a few hours it should be skipped entirely. Too much Ebixa XR can be quite harmful; in fact, emergency medical attention is warranted if too much is taken or it is taken by an unintended recipient, even if no symptoms are apparent.

It takes a month of treatment for significant benefit to be seen, and it may take up to two months (since the first month involves titration) for full benefit to be achieved. Patients are advised to give the medication a couple of months before deciding it doesn't work.

Precautions & Adverse Effects

Serious side effects from Ebixa XR are rare when the medication is used as directed. Most are mild and transient, if experienced at all.

Rarely, however, serious side effects do develop even when great care is taken to administer the medication properly. Seek medical attention if experiencing:

  • Visual, auditory, or tactile hallucinations
  • Severe confusion
  • Severe mood swings
  • Agitation or aggression
  • Seizures

Ebixa XR is known to interact with some other medications, including over-the-counter varieties. While these interactions are not always immediately serious, they can degrade effectiveness over time. Always check with a doctor or pharmacist before mixing medications.

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