Distaclor MR (cefaclor) is a cephalosporin antibiotic which is primarily used to treat infections. Infections must be caused by susceptible bacteria, which in most cases only a doctor can determine. The medication is not effective against all types of bacteria, and will not provide benefit in viral or fungal infections.

The MR in this product's name indicates it is a modified release version, meaning it does not need to be taken as often as regular, fast-acting tablets. However, Distaclor MR tablets also must not be split, chewed, dissolved, or otherwise damaged; doing so destroys its MR properties.

Distaclor MR is sometimes used instead of penicillin when unavailable or otherwise unsuitable. Note, however, that individuals who have had an allergic reaction to penicillin or other cephalosporin antibiotics are likely to have an allergic reaction to Distaclor MR; alternative options are more suitable.

Susceptible Bacteria & Conditions Treated

Distaclor MR is effective against certain bacteria, predominantly:

• Haemophilus influenzae
• Staphylococcal aureus
• Streptococcus pyogenes
• Escherichia coli
• Proteus mirabilis
• Klebsiella spp.

Though less common, it may also be used against certain other bacteria. Likewise it may not always be the best choice for combating the above; in some areas bacterial resistance to Distaclor MR is relatively high.

Very similar infections can also be caused by other bacteria, viruses, or fungi. Ideally patients will have the bacteria identified by a doctor or a lab prior to taking Distaclor MR. As mentioned above, a doctor is best equipped, in most cases, to determine the ideal antibiotic.

The bacteria listed above commonly cause:

• Pharyngitis
• Tonsillitis
• Otitis media
• Skin infections
• Urinary tract infections
• Lower respiratory tract infections
• Other infections when penicillin cannot be taken

Assuming the bacteria is susceptible to Distaclor MR, most patients feel better within a day or two of starting treatment and the infection is completely cleared up within 10 days.

Dosage & Administration

Dosage of Distaclor MR will vary according to what's being treated, its severity, and in some cases personal variables like patient age and weight. Children in particular should be seen by a doctor to get an ideal dosage recommendation.

In the majority of cases involving adults:

• Most patients take 375 mg twice per day, for a total daily dose of 750 mg.
• Pneumonia patients often take 750 mg twice per day, for a total daily dose of 1500 mg.
• Occasionally patients will be instructed to take 500 mg twice per day, for a total dose of 100 mg, though it can be difficult for some to acquire Distaclor MR in this dosage strength.
• Treatment typically lasts for 14 days.
• Some individuals will be instructed to take Distaclor MR for only 7 to 10 days.
• Rarely patients may be instructed to take Distaclor MR for up to 28 days.
• In all cases tablets should be taken with food.

As can be seen from the above, there is a bit of variability in dosage and duration of treatment. Regardless of what it's being taken for, if no serious adverse effects develop then treatment should continue until it's completed, even though the majority of patients will feel perfectly fine before then. Completing treatment ensures there's no lingering bacteria which may resurge after treatment ends, and helps prevent bacterial resistance.

If in doubt, as a general rule antibiotic treatment should continue for a minimum of three days following the resolution of all symptoms.

Potential Side Effects

For the most part Distaclor MR side effects are mild and similar to those experienced with any antibiotic, including:

• Nausea
• Stomach pain
• Vomiting
• Diarrhea
• Headache

The above are not cause for concern unless severe enough to be disruptive. Taking Distaclor MR with food may relieve most of them. Patients with preexisting gastrointestinal issues are at increased risk of experiencing side effects.

Wait at least one hour before or after taking Distaclor MR before taking antacids.

As mentioned above, those who have had an allergic reaction to penicillin or other cephalosporin antibiotics will probably have one to Distaclor MR; it is best avoided for these individuals.

Distaclor MR can interact with other medications. Of particular concern are blood thinners and probenecid, though others can also cause mild complications. Always check with a doctor or pharmacist before taking multiple medications.