|Azulfidine||sulfasalazine||Generic||New Zealand||500mg||400 TAB||RX||$90.00||Add|
|Azulfidine||sulfasalazine||Generic||United Kingdom||500mg||112 Tablets||DR||$34.23||Add|
|Azulfidine||sulfasalazine||Generic||United Kingdom||500mg||336 Tablets||DR||$85.58||Add|
|Azulfidine||sulfasalazine||Generic||United Kingdom||500mg||448 Tablets||DR||$105.55||Add|
|Azulfidine||sulfasalazine||Generic||New Zealand||500mg||100 TAB||RX||$50.00||Add|
Medicines have benefits and some have risks. Always read the label and use only as directed. If symptoms persist or you have side effects see your health professional. Brands and generics both contain the same active ingredient(s) and are medically equivalent. Some brands are marketed under different names by the same manufacturing country depending on the country of origin.
Azulfidine (sulfasalazine) belongs to the disease-modifying antirheumatic drugs (DMARDs) class of medications; how exactly it provides benefit is unclear. The medication is widely used to treat rheumatoid arthritis, and somewhat less commonly in ulcerative colitis and Crohn's disease. It may also be used in related conditions.
In general Azulfidine is used in patients age 6 and up, though it is rarely administered to younger patients. In children dosage is based on weight, which is best determined by a doctor.
Azulfidine is also widely considered safe to take while pregnant, though parents should discuss potential risks with a doctor. Breastfeeding does carry a small risk of serious side effects if taking Azulfidine.
Patients with a history of allergic reaction to aspirin or sulfonamide (also known as sulfa) drugs should not take this product.
In both rheumatoid arthritis and inflammatory bowel disease, Azulfidine will help reduce the severe active effects and, once in remission, will help prolong remission periods. Azulfidine will not cure these conditions, but can significantly improve quality of life.
Dosage does differ depending on if a patient is experiencing an active or remission phase, and to a lesser extent will vary to some degree according to patient response to treatment, and to what is being treated.
For active rheumatoid arthritis:
For rheumatoid arthritis in remission:
For active inflammatory bowel disease:
For inflammatory bowel disease in remission:
Note there are many possible variables that may also influence dosage, including other medications being taken, other medical conditions, patient response, patient weight, and of course patient age---the above guidelines are for adults.
Warnings & Side Effects
About 25 percent of patients react poorly to Azulfidine. The most obvious symptoms are gastrointestinal distress, including:
To some extent the above can be mitigated by taking tablets on a full stomach, but in other patients the above are present regardless, and may become so severe that treatment ends.
More subtle, but also more rare, side effects may also develop:
The above are all severe, and if they begin to develop dosage will be lowered or treatment will end. With the exception of some allergic reactions, all of the above can be detected early if the patient attends regular doctor visits. Again, the above are rare.
Urine color may change to a vivid yellow or orange; this is not cause for concern. Skin can also become yellow or orange; while not necessarily dangerous (yellow skin may also indicate jaundice, however), it can be embarrassing.
Men taking Azulfidine may experience reduced sperm count, which can be so severe as to render a man temporarily infertile. This side effect is completely reversible if treatment ends, however.
Many other medications can interact with Azulfidine, including over-the-counter varieties, many of which are also used to help treat rhuematoid arthritis or inflammatory bowel disease, and consequences can be severe. Always double-check safety with a doctor prior to taking other medications with Azulfidine.