Avomine (promethazine theoclate) is primarily used to reduce or eliminate symptoms of motion sickness, though it also has other relatively common applications, ranging from a sedative to an allergy treatment.

This product should not be used in children under 2 years of age. Children between 2 and 10 should use Avomine only with doctor instruction. Women who are pregnant or breast-feeding should speak with a trusted doctor about possible risks before starting treatment.

Leave Motion Sickness in the Dust with Avomine

Avomine is a simple solution for individuals who suffer from motion sickness, whether it be from automobiles, boats, air travel or other sources. Motion sickness is caused by disturbances in the middle ear, which then send signals to the "vomiting center" (yes, it's really called that!) of the brain which triggers nausea, vomiting, cold sweats, dizziness and similar symptoms. Avomine blocks the signals from reaching the vomiting center, thus eliminating or significantly reducing symptoms.

The medication is most widely available in tablet form. 25 mg is the standard dose, and no more than 4 tablets should be taken per day. Ideally tablets are taken at least 8 hours apart. Administration should be followed by drinking a full glass of water.

When the tablets are taken depends on whether Avomine is being used to prevent symptoms from developing or to alleviate symptoms already being experienced.

To prevent motion sickness:

• For short trips, take one tablet 1 or 2 hours prior to departure. Take another tablet if needed 8 hours later.
• For long trips, take one tablet at bedtime the night before departure. Continue taking one tablet at bedtime for the duration of the trip.
• Additional tablets may be taken as-needed through the day, as long as doses are 8 hours apart.

To treat motion sickness in progress:

• Take one tablet as soon as possible.
• Take additional tablets as-needed every 8 hours.

If taking Avomine to treat existing symptoms, effects should be noticeable in 15 to 30 minutes. The medication is effective for about 8 hours.

Treating Nausea from Other Sources

Avomine is also effective at preventing or alleviating nausea from sources other than motion sickness, including:

• Side effects from other medications
• Balance disorders
• Severe migraines
• Radiation therapy
• Certain diseases

Administration is similar in all cases:

• For prevention, take 1 tablet 1 to 2 hours prior to anticipated illness.
• If ongoing, take 1 tablet at bedtime and additional tablets as-needed during the day.
• For current symptoms, take 1 tablet immediately and additional tablets as-needed every 8 hours.
• Do not exceed 4 tablets per day without doctor instruction.

While some patients use Avomine long-term to treat nausea from a chronic condition, use should not exceed 7 consecutive days without discussing potential risks with a doctor.

Other Uses

The medication may be used in other scenarios; these are typically off-label uses and as such there are no formal dosage & administration guidelines. Avomine may be used:

• As a sedative
• To prevent or reduce allergy symptoms
• To reduce mild pain
• To reduce mild anxiety

Patients interested in Avomine for off-label uses should discuss dosage with a doctor.

Warnings & Side Effects

Like all medications there is a small risk of side effects from Avomine. Usually side effects are mild and not cause for concern, including:

• Drowsiness
• Dry mouth
• Headache
• Mild stomach upset
• Constipation

Rarely some patients experience difficulty urinating while taking Avomine. Stop taking the medication if this side effect is severe enough to be disruptive.

Some patients are at greater risk of experiencing serious side effects, namely those who have:

• Asthma, COPD, or other chronic breathing ailments
• Epilepsy
• Liver or kidney disease
• Heart disease
• Difficulty passing urine
• Glaucoma

The above conditions do not necessarily rule out Avomine use, but patients should discuss risks and possible side effects to be alert for with a doctor before initiating treatment.

Avomine can causes pronounced drowsiness in some individuals. Use caution until effects are known.