Type 2 diabetes is a common disease, affecting over 150 million people worldwide. It is a frightening disease, which has the potential to progress into more serious diseases, and has no known cure. But with exercise, healthy eating and adjunctive therapy medication like Avandia, it is possible for a person suffering from type 2 diabetes to enjoy a fairly normal life.
Avandia works by helping the body respond better to insulin. It is classified as a thiazolidinedione, and as such interacts with the intracellular receptor class of peroxisome proliferator-activated receptors (PPARs). Avandia is the brand name of the standalone version of the drug Rosiglitazone. Its manufacturer, GlaxoSmithKline, also markets Rosiglitazone in combination with metformin (as Avandamet) or with glimepiride (as Avandaryl).
Type 2 diabetes is distinguished from type 1 diabetes in that it is known as "non-insulin-dependent," which means the cells of the body do not respond properly to the presence of insulin. Type 1 diabetes is concerned with the destruction of insulin in the body, which is why type 1 diabetes patients require regular injections of insulin. Type 2 diabetes is primarily a metabolic disorder, which is easily manageable by exercising, balanced dieting and minimizing on drinking and smoking. It is also preventable by leading a healthy lifestyle while still young and less at risk.
However, type 2 diabetes is also known as a precursor of more serious diseases, like heart failure, kidney disease, eye problems that may lead to blindness, nerve damage, skin disorders, gastroparesis (taking too long for the stomach to empty its contents), and depression.
Obesity is a condition that is associated with type 2 diabetes. Weight gain leads to insulin resistance through various means, and the lack of physical activity associated with obesity also contributes to the buildup of insulin resistance witin the body. Children who experience obesity are at an increased risk of developing type 2 diabetes at an early age, although people who are over 40 are considered at greater risk of contracting diabetes than people of any other age.
Who are the people who stand a higher risk of developing type 2 diabetes? People who have a family history of diabetes do, although the onset of diabetes may be prevented by enjoying a healthy lifestyle. People from certain ethnic groups - African Americans, Asian Americans, Pacific Islanders, Hispanics, Latinos and Native Americans, especially - have also been proven to be at higher risk of getting diabetes.
Pregnant women may develop gestational diabetes, which is a form of insulin resistance that is brought about by the rush of hormones caused by pregnancy. Women may also bear babies who weigh more than 9 pounds. Both factors would increase the risk of mothers getting type 2 diabetes later in life. Adjunctive therapy medication like Avandia may be harmful to unborn babies, however, so it would be beneficial to inform your doctor if you are pregnant or if you plan to become pregnant during treatment.
It is worthy of note, however, that Avandia has been associated with serious heart issues. This medicine causes fluid retention, which is known to increase the risk of heart failure. If you or your loved one who is taking Avandia is at risk of developing heart disease, or are suffering from heart problems, it is advisable to consult your doctor before using this medicine.